A comparative study of abnormal intra QRS potentials and high-frequency components in signal-averaged electrocardiogram

Abnormal intra-QRS potentials (AIQP) have been proposed as a promising new index for evaluating the risk of ventricular arrhythmias. However the clinical results are still inconsistent. Our previous study showed that the mean AIQP parameters of ventricular tachycardia (VT) patients were significantly lower than those of normal subjects. Because several previous studies have reported that myocardial infarction and ischemic heart disease could reduce the high-frequency components within the QRS complex, this study will be devoted to comparing the clinical results of AIQP and high-frequency parameters in the diagnosis of VT, and analyzing whether the reduced AIQPs in VT patients are correlated to the changes in high-frequency components. The study results demonstrated that the reductions of AIQP and high-frequency components in VT patients were consistent, and the correlation coefficients between the AIQP and high-frequency parameters were all significant, and ranged from 0.40 to 0.83 (p≪0.05). In conclusion, the significant correlations between the AIQP and high-frequency parameters imply that the reduced AIQP in VT patients is correlated with the reduction of high-frequency components.