Abstract 19083: Predicting Aortic Valve Stenosis Progression: Discordance Between Anatomical and Hemodynamic Assessment of Aortic Valve Severity

Background: The aortic valve area (AVA) is a marker of severity in aortic stenosis (AS) patients and has prognostic and treatment implications. However, there is limited data on predictors of severity progression. Methods: We analyzed 509 consecutive patients with AS who underwent paired echocardiographic studies >180 days apart. Anatomic and haemodynamic assessments of aortic valve stenosis severity were performed. Two hundred and sixty-seven patients (52%) had significant decrease (>20%) in AVA. We compare their baseline echocardiographic parameters to the group without progression. Results: The mean time interval between the paired studies (1252±910 days) and the mean LV ejection fraction (60±12%) were not significantly different between the two groups. One hundred and forty patients (28.8%) had mild AS (defined as AVA >1.5cm2), 217 (44.7%) had moderate AS (AVA 1 - 1.5 cm2) and 129 (26.5%) had severe AS (AVA <1.0 cm2); the decrease in AVA was greatest in those with mild AS (24.7% vs. 10.0% vs. 4.2%, p<...