Interleukin-22 levels are increased in gastrointestinal graft-versus-host disease in children

Interleukin-22 (IL-22) is a member of the IL-10 cytokine family, is induced by many different environmental and endogenous signals,[1][1] and is produced by adaptive and innate immune cells, including innate lymphoid cells (ILCs).[2][2] IL-22 binds to receptors on the epithelial cells of the