Hepatic lesions caused by industrial chemical substances. New perspectives on research

: Many industrial chemicals can be able to interfere with metabolic systems and to damage biological cycle of the cell. However the increasing use of MAC and TLV in occupational toxicology, has greatly reduced the incidence of acute effects; but the problem rose of chronic damage, toxic or carcinogenic, due to a long exposure to chemicals in low doses. The comprehension of functional and anatomical changes occupping in the liver can be of great help in investigation of pathogenetic mechanisms of such effects.