Investigation on hepatitis B virus infection in different populations of Shenyang city

Objective: To investigate hepatitis B virus(HBV) infection in different populations of Shenyang city.Methods:A total of 6974 patients admitted to the hospital were divided into 3 group: group 1(patients aged 14 years and younger),group 2(patients aged 15 years and older),and group 3(pregnant women).HBV serum markers were detected by using enzyme linked immunosorbent assay(ELISA) and compared among 3 groups.Results:The positive rate of HBsAg in group 1 was significantly lower than that in group 2,and the positive rate of anti-HBs in group 1 was significantly higher than that in group 2.No significant difference in HBV infection rate was found between group 2 and group 3.Conclusion:The decrease in the positive rate of HBsAg in children may be the result of universal HBV vaccination.