Abstract 11316: Analytical Validation for an Integrated Risk Tool for Cardiovascular Disease Combining Conventional Risk Factors and Polygenic Risk Inferred from Snp Array and Low-Pass Whole Genome Sequencing

Carla Giner-Delgado,Eva Gradovich,R. Michael Sivley,Karola Rehnström,Andreas Heger,William A. Tarran,Alexander S. Lachapelle,Peter Donnelly,Michael E. Weale,Gilean McVean,Priyanka Seth,Vincent Plagnol

Abstract 11316: Analytical Validation for an Integrated Risk Tool for Cardiovascular Disease Combining Conventional Risk Factors and Polygenic Risk Inferred from Snp Array and Low-Pass Whole Genome Sequencing

2021

Carla Giner-Delgado
Eva Gradovich
R. Michael Sivley
Karola Rehnström
Andreas Heger
William A. Tarran
Alexander S. Lachapelle
Peter Donnelly
Michael E. Weale
Gilean McVean
Priyanka Seth
Vincent Plagnol

Genetic risk factors contribute to cardiovascular disease (CVD) risk and are imperfectly captured by family history. The development of integrated risk tools (IRT) that integrate polygenic risk sco...

Keywords:

Disease
SNP array
polygenic risk score
Genomics
Family history
genetic risk
Whole genome sequencing
Medicine
Computational biology

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations