Method for preparing nimodipine dispersible tablet with high dissolution

The present invention discloses a method for preparing a highly dispersible tablet dissolution of nimodipine, which is to take nimodipine material and a hydrophilic carrier, by melt extrusion techniques, a solid solution thereof, after the solid solution and the amount of pulverized filler , a disintegrant, a lubricant and a surfactant mixed directly compressed into tablets. The preparation method is simple and easy industrial production, fast dispersible tablets prepared nimodipine dissolution rate, in the rapidly disintegrating tablet, the drug in a molecular state immediately release, not only the absorption dose can be improved, but also due to the slow absorption avoids drug metabolic inactivation, the overall result is to maximize the oral bioavailability of nimodipine.