The comparative study - the regenerative effect depends on size of bone graft material in bone loss site around dental implant

Purpose: The purpose of this study is to investigate on the regenerative capacity by using different size of graft materials around bony defect around implant. Material and Methods: Dental implant fixtures(Bio-TIS, Korea) were placed into the tibia of 8 rabbits. After placement of implant, artificial defects were created for each group, and the size of bone graft materials were used according to each designated group. 4 weeks after surgery, 8 rabbits were sacrificed. The histologic and histomorphometrical study were done for comparison of the regenerative capacity using 80-90㎛ and 200∼1000㎛ size of grafting materials of OCS-B Ⓡ . Result: Matured bone formation was significantly increased more in Group E1(80-90㎛) than in Group E2(200∼1000㎛). Group E1(80-90㎛) showed more significant augmentation in marginal length of graft material per unit area than Group E2(200∼1000㎛). Group E1(80-90㎛) showed more interspace in graft material than Group E2(200∼1000㎛). Control group showed no new bone formation around and inside of implanted fixture. Conclusion: Small grafting material size has great influence on bone regeneration. (J Korean Acad Periodontol 2008;38:493-502)