A facile method for urinary phenylalanine measurement on paper-based lab-on-chip for PKU therapy monitoring

A miniaturized paper-based lab-on-chip (LoC) was developed for the facile measurement of urinary Phe (phenylalanine) level on PKU (Phenylketonuria) treated patient. This system permits the monitoring of Phe in a dynamic range concentration of 20–3000 μM.