A no-reflow prediction model in patients with ST-elevation acute myocardial infarction and primary drug-eluting stenting

AbstractObjectives. This study was undertaken to assess independent no-reflow predictors in patients with ST-elevation acute myocardial infarction (STEMI) and primary drug-eluting stenting in the current interventional strategies. Design. One thousand four hundred and thirteen patients with STEMI were successfully treated with primary drug-eluting stenting within 12 h after AMI. All clinical, angiographic and procedural data were collected. Univariate and multivariate logistic regression was used to identify independent no-reflow predictors. Results. The no-reflow was found in 297 (21%) of 1413 patients. Univariate and multivariate logistic regression identified that age (>65 years, OR 1.47, 95% CI 1.46–1.49; p = 0.007), long time-to-reperfusion (>6 h, OR 1.27, 95% CI 1.16–1.40; p = 0.001), admission plasma glucose (>13.0 mmol/L, OR 1.27, 95% CI 1.16–1.40; p = 0.027), collateral circulation (0–1, OR 1.69, 95% CI 1.25–2.29; p = 0.001), pre-PCI thrombus score (≥4, OR 1.36, 95% CI 1.16–1.79; p = 0.011), and ...