Ergolinvázas alkaloidok és analogonjaik enantioszelektív szintézise = Enantioselective total synthesis of ergot alkaloids and analogues
2008
A (+)-lizergsav es az alpha-ergokriptin totalszintezisenek kidolgozasa (J. Org. Chem. 2004, Helv. Chim. Acta, 2005, 2 cikk a Magy. Kem. Folyoiratban, 2006; szabadalmi oltalom, 2004). Negy ergolinvazas klavin-alkaloid [(+)-szetoklavin, (+)-izoszetoklavin,es (-)-9,10-dihidroizoszetoklavin es (-)-dihidroszetoklavin] szintezise (+)-8-oxo-ergolenből kiindulva (Heterocycles, 2006). A lizergsav eszterek uj tipusu dimerizaciojanak megfigyelese es reszletes vizsgalata (Heterocycles, 2007). D-nor-ergolinvazas vegyuletek szintezise, az eddig egyetlen elő nem allitott klavin alkaloid, a (+/-)-cikloklavin totalszintezise (Tetrahedron, 2008). | Total synthesis of (+)-lysergic acid and alpha-ergocryptine (J. Org. Chem., 2004; Helv. Chim. Acta, 2005 and two publications in Magy. Kem. Folyoirat, 2006). Starting from (+)-8-oxo-ergolene synthesis of four clavine alkaloids [(+)-setoclavine, (+)-isosetoclavine, (-)-dihydroisosetoclavine and (-)-dihydrosetoclavine] has been elaborated (Heterocycles, 2006). Observation and detailed study of a new epimerization process of lysergic acid esters. Determination of the mechanism (Heterocycles, 2007). Synthesis of 8-substituted (cyano, alkoxycarbonyl, hydroxymethyl and methyl)-D-norergolenes. Total synthesis of the last so far not synthesized clavine alkaloid, (+/-)-cycloclavine (Tetrahedron, 2008).
Keywords:
- Correction
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI