G411 Audit on the diagnosis and management of congenital hypothyroidism (CHT)

Aim County Durham and Darlington NHS Foundation Trust comprises two district general hospitals and our aim was to audit our practice with national standards in the diagnosis and management of Congenital Hypothyroidism and to obtain outcome data at the age of 3 years. Methods Children diagnosed with CHT over a 10 year period between April 2009 and March 2019 were included in this retrospective study. Data were obtained from electronic records and were compared with the national surveillance data. Results 28 patients were diagnosed with CHT over 10 years that included 11 boys and 17 girls. 23 were term babies. 27 were detected by the new-born blood spot and 1 was diagnosed on antenatal suspicion of septo-optic dysplasia. Out of total 28 referred,1 had a normal venous TSH and so not initiated on treatment.93% were given a trial off thyroxine treatment after their 3rd birthday and 47% had stopped treatment having passed the trial. The compliance with the process and parameter is shown in table 1. National data showed similar sex and gestation distribution in our cohort with better compliance in giving trial off therapy after 3 years of age (table 2). Conclusion The trust has good compliance with national standards and has done better in giving trail off treatment after 3 years. The initial dose of treatment, monitoring blood tests and investigations with scans needs improvement.