Managing hazardous reactions and compounds in process chemistry

1. Managing Hazards for Scale Up of Chemical Manufacturing Processes 2. Safety by Design, The Bedrock for Managing Process Hazards 3. Strategies for Safely Handling Industrial Azide Reactions: The Three Traps 4. Chemical Reaction Safety in the Research Laboratory ? Where It All Begins 5. Systems and Protocols for Evaluating Hazardous Reaction Issues During Early Stage Chemistry 6. Process Safety in the Large-Scale Manufacture of an Adamantane ?-Ketoacid Precursor of Saxagliptin 7. Thermal Risk Assessment: A Powerful Tool for Route Selection for Scale-Up Applied to Diels-Alder Reactions 8. Rapid Scale Up Using Hazardous Reagents: The Challenge of Risk Mitigation 9. Development of a Multi-Kilogram Procedure To Prepare, Use, and Quench Ethyl Diazoacetate 10. Synthesis and Processing of Energetic Materials - Considerations for Safe Scale-up of Potentially Hazardous Reactions 11. Addressing Process Safety Hazards: Replacement of para-Methoxybenzyl Chloride Leads to a Safer and Shorter Route 12. Managing Hazardous Reactions and Compounds in Process Chemistry 13. A New Paradigm in Oxidative Cleavage Reaction: The Use of Continuous Reactors To Enable Safe Scale Up of Ozonolysis 14. Development of Flow Processes for the Syntheses of N-Aryl Pyrazoles and Diethyl Cyclopropane-cis-1,2-dicarboxylate 15. Technology for Continuous Production of Fine Chemicals 16. Continuous Flow Chemistry of Metal Mediated Carboxylation and ?-Arylation Reactions