Method for manufacturing drug eluting stent for benign biliary structure using electrospinning

The invention to that method of manufacturing the drug-eluting stent relates to a method for producing a drug-eluting stent for positive blocking treatment of the bile duct using the electro-spinning is loaded with the polymer solution to the electrospinning apparatus, and perform electrospinning, cover the surface of the stent cover film forming step of forming a film; A first drug layer-forming step of mounting a biocompatible polymer and a drug component to the electrospinning apparatus, and subjected to electrospinning, forming the first drug layer to the cover film thereon; And a second for mounting the biocompatible polymer and is different from the drug and the second drug component formed in the first drug layer component to the electrospinning apparatus, and subjected to electrospinning, to form a second drug layer on the first drug layer drug layer forming step; To include, and thereby provide a technique capable of forming a coating layer uniformly on the surface of the stent. According to the present invention, the coating layer is capable of sustained drug release in the body, so there is an advantage that the treatment effect of the drug is maintained for a long time. In addition, the electrospinning apparatus by not having to replace the nozzle for droplet size by adjusting the size of the drug-containing polymer solution to be ejected from the nozzle it is possible to rapid manufacturing process. In addition, the economic effect, reducing costly drug and polymer solution components of the waste in accordance with the amount as much as the injection of the contained medication required by the electrospinning devices polymer solutions are possible.