[Clinico-morphological evaluation of pathogenetic mechanisms of bouginage and intubation on cicatricial esophageal stenosis after chemical burns].

: The article deals with the clinico-morphological appraisal of bougienage and intubation of patients with cicatricial constriction of the esophagus after chemical burns. Endoscopic and morphological studies were carried out in 38 patients before and during treatment. Bioptic material collected from the esophageal mucosa was studied on a light-optic and ultrastructural level. The results of the study showed that bougienage of the epithelialized strictures causes protracted stimulation of intracellular regenerative processes and thus facilitates the development of leukoplakia of the squamous epithelium. The prevention of esophageal precancer in this case consists in radical maintenance bougienage and regular medical examination. Bougienage of ++non-epithelialized strictures stimulates the formation of young granulation tissue, while subsequent intubation stimulates reparative processes, creating in this manner conditions for adequate epithelialization of the ulcerated esophageal strictures.