Prophylactic Role of Local Gentamicin in Orthopaedics Elective Surgeries: An Observational Study

Introduction: Surgical site infection (SSI) is defined as microbial contamination of the surgical wound within 30 days of an operation or within 1 year after surgery if an implant is placed in a patient. Material and methods: This study includes patient with close fracture of bone, age 18 to 60 years, both male and female. Patients were divided in two groups where three hundred patients enrolled in each group. Written informed consents were taken prior to study. In First group, patients operated during January to March included. These patients not received pre-closure local gentamicin. In second group, patients operated during a period of April to June are included and these patients received injection gentamicin infiltrated locally at surgical operative site during closure. Results: Out of the 600 operated patients included in this study, 31 patients developed infections. The infection rate was 05.16%. Although Infection rate with and without local gentamicin was 03.67% and 06.67% respectively. Conclusion: Implant at fracture site give suitable environment for bacterial growth so strictly preoperative sterilization precautions must be followed in operation theatre and local use of gentamicin at surgical site will helpful to significantly reduced the infection rate.