Synthesis, crystal structure and antimicrobial studies of chlorido(dimethylsulfoxide-κS)(pyrrolidinedithiocarbamato-κ2S,S/)platinum(II)

abstract Article history:Received 20 July 2011Accepted 15 September 2011Available online 24 September 2011Keywords:Platinum(II) complexesPyrrolidinedithiocarbamateX-ray structureAntimicrobial activity Platinum(II)complexes,[Pt(PDTC)(H 2 O)Cl]and[Pt(PDTC)(DMSO)Cl](1)(PDTC=pyrrolidinedithiocarbamate)havebeenpreparedandcharacterizedbyIR,NMRandX-raycrystallographicmethods.Inthecrystalstructureof1 thecentralplatinum atomiscoordinatedto twosulfur atomsofPDTC, onesulfuratomofDMSOandonechlo-rideion adopting a square planargeometrywith theaverage cis and transbondanglesof90.00°and 171.62° re-spectively.The 1 Hand 13 C NMR spectral data indicatethecoordination ofboth PDTC and DMSOtoplatinum(II).The title complex was screened for antimicrobial effects and the results show that it exhibits significant activityagainstgram-negativebacteria(E.coli,P.aeruginosa),whiletheactivitiesaremoderateagainstmolds(A.niger,P.citrinum) and yeasts (C. albicans, S. serevisaiae).© 2011 Elsevier B.V. All rights reserved.