Beliefs About Cancer and Diet among Those Considering Genetic Testing for Colon Cancer

Abstract Objective To assess beliefs about the role of diet in cancer prevention among individuals considering genetic testing for Lynch Syndrome. Design Family-centered, cascade recruitment; baseline assessment of a longitudinal study. Setting Clinical research setting. Participants Participants were 390 persons, ages 18 and older, including persons with a Lynch Syndrome-associated cancer and suspected of carrying a disease causing mutation, and relatives at risk for inheriting a previously identified mutation. Main Outcome Measures Assess clustering of beliefs about the role of diet in cancer prevention and predictors of class membership. Analysis Confirmatory factor analysis; 2-class factor mixture model with binary indicators; multilevel regression analyses, individuals nested within families. Results Women endorsed a relationship between diet and cancer prevention more often than men ( P P P P P Conclusions and Implications Identifying factors associated with a belief in cancer prevention through dietary behaviors can inform targeted interventions.