Long-term impact of chronic hemodialysis on glycemic control and serum lipids in insulin-treated type 2-diabetic patients.

There are only a few data in the literature concerning metabolic control in insulin-treated diabetic patients with end stage renal disease (ESRD). The aim of the study was to find out the long-term impact of hemodialysis on glycemic control and lipid values in type 2 diabetic patients. Twenty insulin-treated type 2 diabetic patients (age 62 ± 9 years, f:m = 6:14) were evaluated. We compared HbA1c, fasting blood glucose (FBG), body weight, serum lipids, insulin requirement, and blood-pressure (BP) 12 and 6 months before dialysis, at the start of dialysis, and 6 as well as 12 months after the start. Results: The mean HbA1c- and FBG-values were not significantly different before and after the start of dialysis therapy. The average insulin requirement was 26 ± 10 IU/day in the predialysis period, 25 ± 12 IU/day at the start, and 24 ± 13 as well as 22 ± 13 IU/day after the start of dialysis. The mean cholesterol level fell significantly from 199 ± 63 and 190 ± 49 mg/dL in the predialysis phase to 167 ± 62 and ...