Zur Frage einer Nebennierenrindensuppression durch Enoximon : eine Probandenuntersuchung mit Dokumentation des hämodynamischen Verlaufs

In contrast to the bipyridine derivatives amrinone and milrinone, the phosphodiesterase III/IV inhibitor enoximone is an imidazolone that creates the possibility of inhibiting adrenal steroid synthesis, as has already been demonstrated for other imidazoles, e.g. ketoconazole and etomidate. To clarify this point we carried out a double-blind sequential study in seven healthy volunteers