Factor group, Spectroscopic and Thermal studies on Creatininium hydrogen oxalate monohydrate

2013 
Creatinine: A chemical waste molecule that is generated from muscle metabolism. Creatinine is produced from creatine, a molecule of major importance for energy production in muscles. Approximately 2% of the body's creatine is converted to creatinine every day. Creatinine is transported through the bloodstream to the kidneys. The kidneys filter out most of the creatinine and dispose of it in the urine. Although it is a waste, creatinine serves a vital diagnostic function. Creatinine has been found to be a fairly reliable indicator of kidney function. As the kidneys become impaired the creatinine will rise. Abnormally high levels of creatinine thus warn of possible malfunction or failure of the kidneys. Because of this biological importance creatinine treated with oxalic acid and the crystals were grown by slow evaporation technique at ambient temperature. The FT-IR and FT-Raman spectra of this crystal have been recorded and analyzed at room temperature. Further, these molecular vibrations are correlated with the different functional groups by factor group analyses, theoretically. A pronounced change is observed in the N–H stretching frequency of the NH2 group. It is proposed that the amide NH2 group is influence by the intermolecular hydrogen bond in this complex. . Thermogravimetric analysis and differential thermal analysis
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