A Case of Familial Central Diabetes Insipidus: The Response of Urinary Prostaglandins to 1-Deamino-8-D-Arginine Vasopressin

AbstractA case of familial central diabetes insipidus and dilatation of the urinary tract is reported. Administration of desmopressin for 1 year improved urinary tract dilatation with a concomitant reduction in urine volume. Urinary cyclic adenosine monophosphate and prostaglandin E2 excretion increased after treatment.