Uridine-5′-Diphosphate Glucose Analogues. 21. Nucleoside Modified Analogues of Antiviral 5′-O-[[[[(α-D-Glucopyranosyl)Oxy Carbonyl]Amino]Sulfonyl]Uridine Derivatives
1986
Abstract A series of uridine modified analogues of antiviral 5′-O-[[[[(α-D-glucopyranosyl) oxy] carbonyl]amno]sulfonyl]uridine derivatives has been synthesized by reaction of suitably protected glucose and glucosamine derivatives with CISO2-N=C=O and thymidine, 2′-deoxyuridine, 3-methyluridine, 5, 6-dihydrouridine and 1-[(2-hydroxyethoxy) methyl] uracil derivatives. The antiviral activity against HSV-1 has been determined.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
8
References
6
Citations
NaN
KQI