Integration of predictive-corrective incompressible SPH and Hodgkin-Huxley based models in the OpenWorm in silico model of C. elegans

OpenWorm is an international collaboration with the aim of producing an integrative computational model of Caenorhabditis elegans to further the understanding of how macroscopic behaviour of the organism emerges from aggregated biophysical processes. A core component of the project involves the integration of electrophysiological modelling and predictive-corrective incompressible smoothed particle hydrodynamics (PCISPH) to model how neuronal and muscle dynamics effect the nematode’s behaviour. Several tools are being utilised and developed in the course of the project: