Multifunctional supramolecular vesicles for combined photothermal/photodynamic/hypoxia-activated chemotherapy

Multifunctional supramolecular vesicles were constructed by self-assembly of water-soluble pillar[5]arene and near infrared-absorbing guest G. They exhibited remarkable antitumor efficacy through simultaneous combination of photothermal, photodynamic and photodynamic-triggered hypoxia-activated chemotherapy.