Tolerability of Interstitial Brachytherapy of the Liver: RILD, Imaging, and Laboratory Monitoring

A key limiting factor in the radiotherapy of liver malignancies is the relatively low tolerance of the liver parenchyma to radiation. This can lead to subclinical focal or generalized injury of the liver parenchyma under radiation treatment. It is of great importance to detect the rare complication of radiation-induced liver disease (RILD) early and to treat it symptomatically, as well as to protect patients with increased risk by preventive medication.