Characterization of solitary pulmonary nodules with 18F-FDG PET/CT relative activity distribution analysis

Objectives To compare the capability of relative activity distribution (RAD), a new index of fluorodeoxyglucose F18 (18F-FDG) uptake, with those of the typical markers for differentiating benign and malignant solitary pulmonary nodules (SPNs) by integrated positron emission tomography (PET)/computed tomography (CT).