Combined Chemotherapy and Irradiation of Pulmonary Metastases in Patients with Renal Adenocarcinoma

In the records of patients treated for renal adenocarcinoma and followed at the Radiumhemmet in Stockholm since 1940, no cases of spontaneous regression of metastases have been observed, either in the lungs or elsewhere. All patients with metastases died of their malignancies. During one period in the 1960s, hormone therapy, mainly provera in high doses, was given to patients with metastases from their primary kidney tumor. A short term objective regression was observed in 1.7% of patients.