A Patient with a Pathological Diagnosis of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP)

Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was proposed in 2016 as a new pathological diagnosis to replace the low-risk histologic diagnosis of noninvasive encapsulated follicular variant of papillary thyroid carcinoma (NIEFVPTC). Development of this new nomenclature specifically omitted the word “cancer” from the name, since these tumors have been shown to have very low malignant potential and affected patients do not benefit from completion thyroidectomy and radioactive iodine (RAI) therapy. NIFTP was subsequently codified as a diagnostic entity by the World Health Organization in 2017.