AB0715 The Frequency of Spondyloarthropathy in Inflammatory Bowel Diseases

Background The most extraintestinal finding of inflammatory bowel diseases is musculoskeletal involvement. “Enteropathic arthritis” has been described as an inflammatory arthritis that gastrointestinal system plays a role in its pathogenesis and occuring with inflammatory bowel disease. Arthritis associated with inflammatory bowel disease effects peripheral and axial joints. Objectives The aim of this study is to evaluate the frequency of spondyloarthropathy and ankylosing spondylitis in inflammatory bowel diseases. Methods 319 patients with inflammatory bowel disease following-up at Ankara University medical faculty gastroenterology department were included in the study. Modified New York criteria and ASAS classification criteria were used for ankylosing spondylitis. European spondyloarthropathy study group (ESSG) criteria were used for enteropathic arthritis group. Descriptive statistical data for continuos variables were presented as median (min–max), % and frequencies were used for categorical variables to summarize of the results of the study. Results The mean age of the patients was as follows; 40.08±12.7 years in Crohn9s disease (CD), 40.0.8±12.4 years in ulcerative colitis (UK). Of the CD patients, 88 (46.3%) was male, 102 (53.7%) was female. 68 (52.7%) male, and 61 (47.3%) female was found in UK patients. HLA-B27 positivity was measured 36 (18.9%) in CD, and 27 (20.9) % in UK. The frequency of entesopathy was observed 32 (24.8%) in UK and 57 (30%) in CD. Anterior uveitis was found 5 (2.6%) in CD and 4 (3.1%) in UK. Of the patients, 55 (28.9%) CD patients and 29 (22.5%) UK patients had active smoking history. Positive family history was described 39 (20.5%) in CD and 23 (17.8%) in UK patients. AS was found 26 (13.7%) in CD and 10 (7.8%) in UK. In over all inflammatory bowel disease patients, the frequency of peripeheral arthritis was 49 (15.4%), AS was 36 (11.3) %, and SpA was 61 (19.1%). Conclusions The bowel can be affected different manifestations in IBD. In particular, musculoskeletal involvement may be the first findings of the disease. The frequency of AS was found as 11.3% and SpA was found 19.1% according to our single center experience. Disclosure of Interest None declared DOI 10.1136/annrheumdis-2014-eular.5709