Prognostic relevance of karyometric and histometric features of malignant tumors

In contrast to cytophotomnetric studies of nuclear detail quantitative inorphomnetry of histologic specimens has only been developed to a limited degree as a diagnostic tool /13/. Counting of mnitoses is one of the oldest methods for quantification and has become a valuable predictor of good or poor prognosis of uterine soft tissue tumors /5/. In case of malignant melanoma the determination of tumor thickness has proven an important prognostic factor /4/. Measurements of endometrial gland volume enable the pathologist to discriminate endomnetrial carcinoma from hyperplasia /1/2/. Other applications of mnorphometry to special diagnostic problems could be added /13/. L© (1990) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.