Advanced neural interfaces and drug delivery

Here we report recent advances in precise engineering to incorporate advanced electrophoretic drug delivery system into implantable devices for treating neurological disorders including both depth probes and cortical arrays with recording capabilities. The efficacy of the platform is demonstrated by stopping epileptic seizures in vivo. This is the first in vivo demonstration of an electrophoretic implant treating a neurological disorder and offers a glimpse of what can be achieved by tailored engineering of electrophoretic devices. We anticipate this work to be the starting point for new stimulation, recording and drug delivery paradigms in chronic neural implantation.