One kind tot Luoding Cheng hydrogel membrane preparation and preparation method
2013
The present invention discloses a membrane tot Luoding Cheng hydrogel formulation, tolterodine tartrate prepared directly using Carbomer 980 is mixed with hydroxypropylcellulose gelling agent, water and ethanol as the solvent, hydroxypropyl methylcellulose cellulose-based film-forming agent, Tween 80 as the mechanical film strength modifiers, triethanolamine as pH tot Luoding Cheng membrane hydrogel formulations and drug modulators of transforming agent. 4-10% drug loading, transparent gels, the drug uniformly dispersed, can be applied to the transparent pharmaceutical film applicator volume of less than 0.5ml. When using the sustained release pharmaceutical smoothly for 24 hours, greater than 20% bioavailability. Gel preparation smooth, glistening, smooth, no foreign body sensation after using the skin, long-lasting slow release of the drug, good percutaneous absorption effect, ease of use, improved patient compliance.
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