A new cucurbitacin from Picria fel-terrae

A new cucurbitacin, picfeltarraenone II (1) as well as four known cucurbitacins, picfeltarraegenin I (2), picfeltarraenin IA (3), picfeltarraenin IB (4), and picfeltarraenin IV (5), have been isolated and characterized from the whole plant of Picria fel-terrae. The purity of picfeltarraenin IA has been determined by TLC and HPLC.