Clinical features and management of carboplatin-related hypersensitivity reactions in pediatric low-grade glioma.
2012
Purpose
The effectiveness of carboplatin and vincristine chemotherapy in the treatment of low-grade glioma (LGG) is well established. However, carboplatin hypersensitivity reactions (CHR) are a major problem leading to premature cessation of therapy. We aimed to investigate the clinical features and the management strategies in CHR, retrospectively.
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