Патоморфология каротидного бассейна в генезе ишемического инсульта

2009 
Revealing of frequency and character of lesion of basin of a carotid in a population in connection with ischSummary. Th e revealing of frequency and character of lesion of carotid basin in a population in connection with ischemic stroke (IS) has been studied. Th e material of the research were 670 consecutive autopsies for the 2006 year. Th ere have been studied the degree and character of atherosclerotic defeat of carotids, structure of Wilis circle, markers of cardioembolism. Th e methods of morphometry, histological and histochemical research of arteries and microvessels have been used. A macroscopical estimation of atherosclerotic plaque (AP) has been conducted. The results were: frequency of stenotic defeats of internal carotid (ACI) in the investigated population amounted to 77%. Development of IS is authentically connected with a stenosis of mouth ACI at its size > 80%. At III and IY stages of development of plaque ACI attributes of atheroembolia in foci of IS have been revealed in 52% of the patients. The high importance of cardioembolism of arteries of a brain and anomaly of Wilis circle in development of ischemic stroke have not been confi rmed.
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