Branchiogenic carcinoma arising in the submandibular region: Report of a case

1991 
This article describes a case of the branchiogenic carcinoma arising in the submandibular region of a 52-year-old male. The patient was referred to us with a chief complaint of the submandibular swelling. The tumor was disclosed to be malignant by fine needle biopsy. As the tumor adhered to the basis of the mandible, it was resected including its surrounding normal tissues with a segmental resection of the mandible. The patient was given a postoperative radiation therapy. Although he was followed for 4 years uneventfully, metastatic lesions then appeared in the lungs, leading to his death.A large cystic space was seen in the surgical specimen. The tumor which developed around the cystic space was histologically revealed to be a squamous cell carcinoma. Squamous epithelium remained in some places of the cystic surface and they continued to the tumor tissues. Lymphoid tissue was noted in the stroma of the tumor. From these histological findings, the case was diagnosed as branchiogenic carcinoma.
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