High-throughput, image-based screening of pooled genetic-variant libraries

George Emanuel,Jeffrey R. Moffitt,Xiaowei Zhuang

High-throughput, image-based screening of pooled genetic-variant libraries

2017

George Emanuel
Jeffrey R. Moffitt
Xiaowei Zhuang

Multiplexed FISH readout of barcoded genotypes in single cells allows pooled screening of large genetic-variant libraries for complex, image-based phenotypes.

Keywords:

Molecular biology
Genetics
Bioinformatics
Genotype
Throughput
Systems biology
Biology
Fluorescence in situ hybridization
genetic variants
image based
fluorescent protein
screening method
Genotyping

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