PAI-1 Promoter Polymorphism Modulates uPA-PAI Complex Accumulation by Breast Cancer Cells

Juan J. Álvarez-Millán,Carlos Bocos,V. Ferrín,A.R. Lucas,A. Ruibal,J. Schneider

PAI-1 Promoter Polymorphism Modulates uPA-PAI Complex Accumulation by Breast Cancer Cells

2002

Juan J. Álvarez-Millán
Carlos Bocos
V. Ferrín
A.R. Lucas
A. Ruibal
J. Schneider

Objectives: The uPA-PAI system has been shown to play a role in the development of a more aggressive tumor phenotype. The PAI-1 promoter 4G/5G polymorphism, furthermore, regulates f

Keywords:

Immunology
Breast cancer
Plasminogen activator inhibitor-1
Cancer
Cellular differentiation
Phenotype
Polymorphism (computer science)
Promoter
Cancer research
Immunohistochemistry
Biology
Genotype

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