Organs-on-a-Chip

Organs-on-a-chip are microfluidic cell and tissue culture platforms capable of recapitulating key physiologies and functions of specific organs for further biological and medical purposes. A considerable number of such devices have been developed for many different organs such as blood vessels, lung, and liver. The development of organ-on-a-chip devices has helped widen our understanding of biological phenomena. Beyond basic science, organ-on-a-chip devices have also contributed to pharmacological studies. Despite the many outstanding achievements of previous organ-on-a-chip studies, there is still room for further improvement such as the improved modeling of fundamental organ processes as well as integration of individual organ modules into a generalizable human-on-a-chip.