Thrombotic Thrombocytopenic Purpura Associated with Cyclocyporin Use in a Liver Transplant Patient

Many complications may develop due to immunosuppressive drugs given to patients with liver transplantation. Thrombotic microangiopathy (TMA), which is one of those complications, is encountered very rarely and if untreated, it endangers life. When we reviewed the literature, we came across to a few thrombotic thrombocytopenic purpura (TTP) cases, which have developed due to calcineurin inhibitor use after the liver transplantation. And according to our knowledge, this present case was the first TTP case, which occurred due to cyclosporine use after the liver transplantation. While our patient with liver transplantation was receiving cyclosporine, clinical picture of TTP was developed, and the disease was controlled by using pulse steroid and performing plasma exchange treatment.