A Synthesis of N-Substituted β-Alanines: Michael Addition of Amines to Trimethylsilyl Acrylate

Stefan Kwiatkowski,Azhwarsamy Jeganathan,T. Tobin,David S. Watt

A Synthesis of N-Substituted β-Alanines: Michael Addition of Amines to Trimethylsilyl Acrylate

1989

Stefan Kwiatkowski
Azhwarsamy Jeganathan
T. Tobin
David S. Watt

The Michael addition of primary and secondary amines 2 to trimethylsilyl acrylate (1) afforded β-(alkylamino)- and β-(dialkylamino)-propionic acids 4, respectively, in good yield

Keywords:

Acrylate
Photochemistry
Trimethylsilyl
Organic chemistry
Aliphatic compound
Steroid
Michael reaction
Chemistry

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