Conversion of N-acetyl-d-glucosamine to nitrogen-containing chemicals in high-temperature water

Abstract To demonstrate the conversion of renewable biomass to platform chemicals, we previously reported the noncatalytic conversion of N -acetyl- d -glucosamine (GlcNAc), which is obtained from chitin, to nitrogen-containing chemicals; however, various aspects of this process were not clarified. Herein, we reported updated and expanded results for the synthesis of nitrogen-containing chemicals from GlcNAc in high-temperature water at 180–280 °C and 25 MPa with a reaction time of 5–34 s. The main products were 2-acetamido-2,3-dideoxy- d -erythro-hex-2-enofuranose (Chromogen I) and 3-acetamido-5-(1′,2′-dihydroxyethyl)furan (Chromogen III) with the maximum yields of 37.0% and 34.5%, respectively. Although 3-acetamido-5-acetylfuran was expected to form by the dehydration of Chromogen III, a yield of only