Synthesis of thymine, cytosine, adenine, and guanine containing N-Fmoc protected amino acids: Building blocks for construction of novel oligonucleotide backbone analogs

Abstract A convenient synthesis is described for thymine, cytosine, adenine, and guanine containing, glucosamine-based N-Fmoc protected amino acids. These molecules are building blocks for the construction of novel oligonucleotide analogs via N-Fmoc type peptide chemistry.