The effect of fructose infusion on the levels of blood glucose and insulin in T2DM

Objective To evaluate the effects of fructose infusion on the levels of serum glucose and insulin.Methods Sixty nine cases with T2DM were randomized into the daily 3 hour infusion of 500 ml of 5% fructose(n=35) and normal saline(NS,n=34) respectively.The levels of serum glucose and insulin were assayed at 0,1.5 and 3 hour of infusion;and uric acid levels,at 0 and 3 hour.Results There were no differences in serum glucose and insulin or uric acid between infusion of fructose and NS at 0,1.5,and 3 hour of infusions. Conclusion The fructose infusion does not affect the levels of serum glucose,insulin and uric acid,as compared with NS infusion.