Evidence-based interventions for the management of oral mucositis among cancer patients

Objective To establish a high-quality and evidence-based interventions for management of oral mucositis on cancer patients who received chemo-radio therapy in Chinese clinical status. Methods Under the guidance of knowledge-to-action （KTA） process framework, we retrieved all evidence in evidence-based health care databases by the method of a structured search of the literature. Through reviewed and analysed the quality of literature and analysed national health environment, we synthesized, distilled and refined the evidence into best practice interventions according to JBI Best Practice Information Sheet author guideline and JBI- developed 2010 Grades of Effectiveness and levels of evidence. All interventions evaluated by relative experts and focus-group-discussion. Results After assessed the quality of literature, there were three articles that had been collected by the guideline of evidence based clinical practice, fourteen by systematically assessment, one by investigation report of current multicentric status, added three expert＇ s literature review or opinion, one evidence literature review. That all collected information had been formed four best information practice manual and one evidence-based summary. To establish the evidence-based nursing interventions for oral mucositis should include oral assessment process, oral care process, the pamphlet of patient education, basic oral care technique and quality audit standards. Conclusions Through the process of interventions＇ establishment, scientific credible and rigorous attitudes guided. Interventions supported by abundant evidence to ensure that they were practical, economical and suitable to manage and guide oral mucositis among cancer patients in Chinese clinical. Key words: Tumor;  Oral mucositis ;  Evidence-based practice ;  Radiotherapy;  Chemotherapy;  Plan constructed