MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development

Xingwang Xie,Xueyan Wang,Weijia Liao,Ran Fei,Nan Wu,Xu Cong,Qian Chen,Lai Wei,Yu Wang,Hong-Song Chen

MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development

2018

Xingwang Xie
Xueyan Wang
Weijia Liao
Ran Fei
Nan Wu
Xu Cong
Qian Chen
Lai Wei
Yu Wang
Hong-Song Chen

Background Identification of novel MDM2 or p53 binding proteins may reveal undefined oncogenes, tumor suppressors, signaling pathways and possible treatment targets.

Keywords:

Suppressor
Cancer research
Biology
MYL6B
Apoptosis
Myosin light-chain kinase
Mdm2
Signal transduction
P53 binding
Immunoprecipitation
Myosin
Proto-Oncogene Proteins c-mdm2

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