Simple and Efficient One-Pot Three-Component, Solvent-Free Synthesis of β-Enaminones via Sonogashira Coupling—Michael Addition Sequences.

Abstract A simple, efficient, and environmentally friendly one‐pot, three‐component synthesis of β‐enaminones via Sonogashira coupling–Michael addition sequences under solvent‐free conditions has been reported. Also the synthesis of β‐enaminones has been achieved in high yields by the direct reaction of amines with ynones under solvent‐free conditions.