Derivatives of 1H-tetrahydrobenzodiazepine-1,5.
1982
: Synthesis of acyl derivatives of 2-aminomethylene-4-phenyl-1H-tetrahydrobenzodiazepine-1,5: compounds 5, 7 and 8, of a Schiff base 6 acids 9 and 10, and esters of aryl- or alkyl-1H-tetrahydro-1,5-benzodiazepine-2-carboxylic acids 11-14 is described. Compounds 9-13 showed potent antagonism towards pentetrazol, and compound 13 also potentiated the action of DOPA and had antiserotonin properties.
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