Synergy between sacubitril and valsartan leads to hemodynamic, antifibrotic, and exercise tolerance benefits in rats with preexisting heart failure

Mikhail Y. Maslov,Stephan Foianini,Dita Mayer,Michael V. Orlov,Mark A. Lovich

Synergy between sacubitril and valsartan leads to hemodynamic, antifibrotic, and exercise tolerance benefits in rats with preexisting heart failure

2019

Mikhail Y. Maslov
Stephan Foianini
Dita Mayer
Michael V. Orlov
Mark A. Lovich

Our data suggest the following explanation for the effects of sacubitril/valsartan: 1) synergy of sacubitril and valsartan leads to the improvement of load-dependent left ventricular contractility ...

Keywords:

Valsartan
Sacubitril, Valsartan
Biochemistry
Hemodynamics
Volume overload
Contractility
Heart failure
Sacubitril
Cardiac function curve
Internal medicine
Biology
Cardiology
Diabetes mellitus

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